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The sound-quality is this picture quality.

Here’s a quick clip of our bassist Mike Carlo and his brother Chris covering Nirvana’s “About A Girl” on GarageBand. Enjoy?

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The key to a great album? Drinking plenty of water.

Hey guys. How have you been? We’ve been great; not that you were asking anyway. Why don’t you call anymore? Your mother’s worried sick and you know she makes your favorite lasagna on Sundays.

We’ve been hunkered down the past few weeks recording our new album with the always-classy and amazing Joe Pecora. If you are interested in seeing our baby be birthed in real-time (forget that mental image), head over to where you can read about us recording, see pics of us recording, and even WATCH us recording!

Also, just because we’re busy recording doesn’t mean we’re slowing down our party performing game. We’ve got a few shows already locked-in for March with more dates on the way in the near future.

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Don’t forget, we’re also on , , , , ; Well, maybe not Fetlife…yet!cialis free

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Merry Christmas!

You there, boy!
… or girl,

We don’t want to take up much of your time on this busy day full of feasting and family and fun and festivities and f-words, so we’ll make this quick.

Please enjoy this LES VINYL HOLIDAY SAMPLER: cialis free

It’s a selection of songs from our full length LP – Bright Gray – as well as, our EP – Nafia Mail. PLUS a very special ‘holiday version’ of our new song, “SIDEKICK.”

Please feel free to re-gift this. It makes a great inbox stuffer.

For more info please “surf” our website or check us out on Facebook () and Twitter (). We also use morse code.

Eternally yours,
Les Vinyl

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File-photo from Maxwell's show earlier this year.

We suuuuure hope so! Boy, are we happy to see you!

We just wanted to throw a quick update up here to say how much fun we had last night at Maxwell’s. We love Kevin Devine and the whole Goddamn Band and loved playing with them. Maxwell’s is the greatest place to play and we had a great time talking to and meeting new friends and fans. For everyone that signed the mailing list: HOORAY!! THANKS!! We will send out a mailing list email real soon with our free Nafia Mail EP, show dates, and other fun stuff. cialis freeCool? Cool!!

Thanks again, ladies and germs (HAHA).

See you in the internet,
Les Vinyl (Jenny, Casey, Michael, Pat)

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Clearly, performing on top of this giant turkey is our next logical goal. Vinylos, you have your orders.

Dearest Les Vinyl-ites, we have much news and information to share with you. First things first, what do you think of “Les Vinyl-ites?” It’s a little weird, right? We’re trying to work on a good collective fan name. I mean, even , we ought to have Vinylos. Vinylos!

Ok, more serious business. We would like to seriously thank everyone who voted for us in the NYC Band of the Month contest. If you were one of the many people who voted from your home, work, and friend’s computers, and then forced your friends to do the same thing, and then forced strangers at Starbucks to do the same, we love you endlessly. We finished the contest with close to 250 votes. We’re amazed and super grateful to all who helped us to get the word out. Unfortunately, though, we did not win the contest. Congratulations to the winner, ; and congratulations to all the artists chosen to be in the contest. Les Vinyl condones your listening to all of them. The contest taught us that we have to really step up our game as far as exposure to the NYC area outside of our own circle of friends. We want to entice strangers with our musical ear candy and coax them into our van (filled with Vinylos!). Poor attempt at a joke. And a really abstract one, at that. Anyway, huge thanks to all of you!!

Oh oh! We just wanted to scream like little girls and tell you that the on December 17th is officially SOLD OUT. If you didn’t get your tickets yet, we’re sorry. You’re gonna miss quite a night. We’re so excited!!

Finally, a few other things happening soon:
-This Wednesday (11/24), we are playing at Cargo Cafe in Staten Island with Ghost Bunny and Paragraph to celebrate Thanksgiving Eve. It’s going to be an insane party, you should really be there.

-Saturday December 4th is the Mid-Evenings with Jay Miller Holiday Special. This show is near and dear to our hearts (considering Jenny is the Production Manager and Casey is a writer and prominent cast member!); if you haven’t seen the show yet, all episodes are up for free at . You’ll wanna buy your tickets for 12/4 about halfway through the first episode you watch, so get on that as soon as they become available.
-A day later (a whole day!) we’ll be playing in BK. Night starts at 7pm, other acts TBA ASAP (BYOBFTB! [Buy your own beer from the bar])!
-LV starts recording a second album super soon! We have so many new songs that we love so much and can’t wait to show them off!

My fingers hurt from talking so much.
We love you! Happy Thanksgiving!
Les Vinyl (Jenny, Casey, Pat, Michael)

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Hey everybody!

We’ve got some exciting news! This past week we were placed into a poll on the prestigious web site! We need every single one of you to vote for us. Why? Because if we win, we get a big article about us and a giant top-banner with our picture on it for the entire month of December (+ other cool stuff)!

Show your love for Les Vinyl and go and vote on the right side of the main page for Les Vinyl asap! Tell your friends, tell your enemies, tell complete strangers! We need everyone to get out the vote! You can vote once per IP address and voting ends on the 15th.

If we win we’ll definitely try and come up with some awesome way to thank you guys. We don’t know exactly what yet because this contest was very, and delightfully, impromptu; but if you’re somehow on the fence about voting, trust that if we win we’ll make it worth your while!

Big thanks to everyone who has voted so far! This race is WAY too close to give up now! So go VOTE VOTE VOTE!

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Hey guys! We’ve got a very special Phat Tuesday for you because we’re giving you two FREE songs! FOR FREE!

Both are covers that were recorded way back over a year ago when we played The Greenbelt concert series for local radio station .

The first song is a cover of one of our favorite Matt Wilson songs, “Water.” If you haven’t heard Matt Wilson before, run (don’t walk) over to his website, , and download some free music and give a listen.

The second song is a cover of the Animal Collective song “Doggy.” You can check them out , but don’t steal any of their music because it’s not for free. ::cough torrents ::cough::

We hope you enjoy our covers and be sure to come out to the Wonder Bar in Asbury Park tonight and check us out there. We’ll also be playing the 17th at Union Hall, as well as December 17th at Maxwell’s with (get your tickets for THAT )

Download:

Download:

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Hey gang!

Over the past few month, Les Vinyl’s “” album has seen some serious airplay on the college circuit.

With the CMJ Festival this week, and Les Vinyl , the 23rd, at noon-ish for the showcase, we’d like to take this time to thank all of the college stations who have been playing Les Vinyl as well as all of the new fans who have been enjoying us being played on such big airplay supporters like [Ohio], [Washington], [Florida], and [New Jersey] as well as a boatload more!

With your help we were able to chart at #188 on the CMJ 200!

Thanks so much for supporting us, guys! If you’d like to go the extra-mile to support us and send this to important people or are a college station or website looking for info on us, , which can also be found and downloaded on our “About” page.

As a thank you, here is a very special Phat Tuesday video. It’s a video clip of the song “Sink” from the filmed by director at in Staten Island during this year’s “Bright Gray” release party. It was on the site, like, five months ago for about a week and was then mysteriously taken off Vimeo.

But now it’s back for good! Enjoy!

Also, don’t forget Les Vinyl have a couple of other big shows coming up in November. On the 2nd the band is playing the Wonder Bar in Asbury Park, NJ and on the 17th will be playing Union Hall in NYC.

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It’s time again for another new video from Les Vinyl.

Kanye West might have bitched-out on giving you a new GOOD Friday track, but we would never bitch-out on you. We’re not some kind-of gaggle of bitches or something.

Here is Les Vinyl performing “Espiritu Santos” off …. LIVE!

Stay tuned to Lesvinyl.com because we’ve got a bunch of announcements coming later this week that are super-awesome, just like you! Come back and let’s be super-awesome together! Unless you just wanna stay friends for now; it’s cool, we’re mature enough to handle it. We can take it slow, no rush. As long as we can still get to second-base, errthing’s aiight.

MONDAY, May 12 (HealthDay News) -- Patients with Duchenne muscular dystrophy often suffer from heart failure, but Viagra might prevent or delay the onset of this condition, a new Canadian study finds. Workers in the BPA factories were four times more likely to report erectile dysfunction, reduced sexual desire and overall dissatisfaction with their sex life. They were also seven times more likely to have ejaculation difficulties. The first published efficacy trial of sildenafil involved only 12 patients, but it is the only study that included objective measurements of penile rigidity.20 In the first phase of this study, penile rigidity was measured using plethysmography during visual sexual stimulation in patients taking varying doses of sildenafil or placebo. In the men who took the 50-mg dose of sildenafil, the mean duration of erection was increased by 10 minutes at the base of the penis and six minutes at the tip of the penis compared with placebo. The second phase of this study involved a diary of erectile activity in which 10 of 12 patients reported improved erectile activity while receiving sildenafil. Easily hidden and transportable ?2 Note that the number of functional enzymes in most species may not equal the number of gene products. For example, the major rod cell photoreceptor PDE6 exists as a heterodimer of two different gene products, PDE6A and PDE6B. The cone photoreceptor cell PDE6 consists of a homodimeric PDE6C. In some species, such as chickens, the rod enzyme may be a PDE6B homodimer. Thus, it is not clear whether each gene that contains a conserved catalytic sequence should be classified separately as a different PDE. real viagra without a prescription Patients A total of 268 men (mean age, 57 years) with erectile dysfunction (mean duration, 5.6 years) and diabetes (mean duration, 12 years). Fatigue Changes in appetite The latest Erectile Dysfunction News & Premature Ejaculation News articles published daily. Includes news on erection difficulties, treatment options and causes. Men taking high doses of ketoconazole (Nizoral) should not take more than 2.5 mg of vardenafil in a 24-hour period. FPRIVATE "TYPE=PICT;ALT=diaphragm - cervical cap" Description: The American College of Physicians developed this guideline to present the available evidence on hormonal testing in and pharmacologic management of erectile dysfunction. Current pharmacologic therapies include phosphodiesterase-5 (PDE-5) inhibitors, such as sildenafil, vardenafil, tadalafil, mirodenafil, and udenafil, and hormonal treatment. The following cell lines were used: CT26, a carcinogen-induced, undifferentiated colon carcinoma obtained from BALB/c mice (51); TS/A, a mouse mammary adenocarcinoma derived from BALB/c mice (52); MCA203, a C57BL/6-derived fibrosarcoma (53); and B16-GM, a C57BL/6 melanoma cell line genetically modified to secrete GM-CSF (54). The 4T1-HA cell line was obtained by lentiviral transduction of 4T1 mammary carcinoma and was provided by K. Whartenby (Johns Hopkins University, Baltimore, MD). These cell lines were grown in DMEM or RPMI 1640 (Invitrogen) with 10% FBS (Invitrogen). The C26GM cell line derived from the C26 colon carcinoma was genetically modified to produce GM-CSF (8) and was grown in the presence of 800 µg/ml G418. To exert a measurable antitumor effect, tumor-specific T cells must be present in sufficient numbers and capable of trafficking to their targets. A direct correlation exists between the number of tumor-infiltrating lymphocytes (TILs) and a favorable clinical outcome, as demonstrated in patients with metastatic ovarian cancer (20). Furthermore, the functional status of TILs has been correlated with a favorable prognosis in various human malignancies (20–24). Because PDE5 inhibition augments antitumor immunity, we asked whether sildenafil treatment altered both the number and activation state of TILs. Histological examination of CT26WT tumors revealed a greater intratumoral cellular infiltrate in the sildenafil-treated mice compared with the untreated controls (Fig. 4 A). To better evaluate these differences, C26GM-bearing mice received either tumor-primed or no T cells followed by sildenafil treatment or no additional therapy. The tumors were excised 9 d later, and single cell suspensions were obtained. The T cell infiltrate was analyzed by flow cytometry for CD4+ and CD8+ T cells. This approach enabled us to accurately examine the entire tumor mass and reliably quantify the infiltrating lymphocytic population. Although no increase in CD4+ T cells was observed with PDE5 inhibition (Fig. 4 B, inset), sildenafil treatment greatly increased CD8+ intratumoral infiltration with up-regulation of the activation markers CD69 and CD25 (Fig. 4 C). There were no differences in activation markers between the sildenafil-treated group and sildenafil + ACT, whereas a significant increase in intratumoral T cells were observed in the sildenafil + ACT–treated group compared with sildenafil alone (Fig. 4 B and Fig. S4, available at http://www.jem.org/cgi/content/full/jem.20061104/DC1). The types of medications can be divided into oral, topical, injectable, and intraurethral insertion. Sildenafil (Viagra) Almost immediately after the discovery of cAMP by Sutherland and colleagues, cyclic nucleotide PDE activity was described (Butcher and Sutherland, 1962). With the subsequent discovery of cGMP, it was found that both cAMP and cGMP could be hydrolyzed by the same type of activity, i.e., hydrolysis of the 3? cyclic phosphate bond. On the basis of substrate competition studies, it was clear that at least some of these activities must have the same catalytic site. In fact, many of the early studies on cyclic nucleotides were directed toward understanding PDE activity since at that time it was much easier to measure PDE activity than either cAMP or cGMP themselves or the enzymes that catalyzed their synthesis. With the advent of assays using radioactive substrate, it became clear that there were likely to be multiple forms of PDEs with different kinetic and regulatory properties (Thompson et al., 1979; Beavo et al., 1982). However, it was not until higher resolution fractionation techniques, monoclonal antibodies, and molecular cloning and sequencing procedures were applied to the PDEs that the truly large number of different gene products was fully appreciated. How Erectile Dysfunction Works canadian pharmacy viagra

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